07:30

Registration & Breakfast

Hinxton Hall Conference Center at The Wellcome Genome Campus

08:30

Welcome by Pablo Legorreta, Founder and Chief Executive Officer of Royalty Pharma

08:35

Welcome by Deborah Prentice, Vice Chancellor of University of Cambridge

08:40

Expanding the Druggable Genome with Small Molecules

Nello Mainolfi (Kymera)
Hosted by Karen Akinsanya (Schrödinger)

09:00

Sourcing Innovation Across Academia, Biotech, and Pharma

Mary Lynne Hedley (Third Rock), Carol Gallagher (formerly NEA), Deborah Baron (Pfizer)
Hosted by George Golumbeski (DROIA)

09:30

Discovery Stories and Technologies: Single Cells to AI

Roger Perlmutter (Eikon), Mark Kotter (University of Cambridge), David Reese (Amgen)
Chaired by Abraham Heifets (Atomwise)

10:25

Refreshment Break

10:50

Public Investors Weigh In on The Market and Current Innovation

Rajiv Kaul (Fidelity), Andy Acker (Janus Henderson), Phill Gross (Adage)
Hosted by Terry Coyne (Royalty Pharma)

11:30

Every Breath You Take: Oxygen Sensing and Where it Leads Us

Peter Ratcliffe (University of Oxford)
Fireside Patrick Maxwell (University of Cambridge)

12:05

The New Weight Loss Drugs and Their Global Impact on Obesity

Karin Conde-Knape (Novo Nordisk)
Hosted by Brienne Kugler (Royalty Pharma)

12:25

Decoding a Billion

Shankar Balasubramanian (University of Cambridge)
Fireside chat with Siddhartha Mukherjee (Columbia University)

13:00

Lunch

13:45

Using Yale Science to Hijack your Liver:
Biohaven’s New Approach to Immune-Mediated Diseases

David Spiegel (Yale University)
Hosted by Marshall Urist (Royalty Pharma)

14:05

Will R&D Ever Deliver and, if so, Where the Hell is it Going?

Christian Rommel (Bayer), Mene Pangalos (formerly AstraZeneca)
Hosted by John Maraganore (formerly Alnylam)

14:35

CAR-T Cell Therapy in Autoimmune Disease

Georg Schett (FAU Erlangen Nürnberg)
Hosted by Jim Reddoch (Royalty Pharma)

14:55

Development of an Antisense Drug for a Deadly Neurodegenerative Disease

Adrian Krainer (Cold Spring Harbor Laboratory)
Hosted by Julia Alterman (UMass Chan Medical School)

15:15

Refreshment Break

15:30

Novel Oncology Approaches

Jak Knowles (Affini-T Therapeutics), Troy Wilson (Kura Oncology), Zachary Hornby (Boundless Bio)
Chaired by Padmanee Sharma (MD Anderson)

16:25

Paying for Innovation

Jeffrey Berkowitz (Real Endpoints)
Hosted by Rachel Mears (Jeito Capital)

16:45

Private Markets and Mergers: Heating Up or Overheated?

Francesco De Rubertis (Medicxi), Otello Stampacchia (Omega), Srini Akkaraju (Samsara)
Hosted by Oleg Nodelman (EcoR1)

17:20

End of Day One Program

18:30

Recital and Dinner at King’s College